Hi – here’s a fun lab-based representation of the circadian clock! It’s been put together using everyday bits-and-pieces found in the lab, and includes things that oscillate, or cycle, and there’s also a balance to represent clock compensation. There’s also some quite random things to add to the concept of the clock responding to chaos. The sculpture has been developed as part of Ally Wallace’s Art-Science collaboration with the Nimmo lab, funded by the Leverhulme Trust. Check out the link, here, for more details.
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The RNA Journal is twenty years old and as part of their anniversary around 130 researchers in the field of RNA biology have contributed some of their personal reflections of working in this area. Contributors include Douglas Black, Michael Rosbash and Alberto Kornblihtt.
I’ve browsed through some of the essays and one that caught my attention was ‘Thoughts on NGS, alternative splicing and what we still need to know‘ by Kristen Lynch. Here she emphasises the need to determine the functional consequences of alternative splicing for an organism, and as she pointedly says ‘To truly appreciate the full impact of alternative splicing on biologic processes, and argue against those who wonder if it might all be “noise,” we need to do better. The question is how to achieve this goal’. [Note that NGS in the title of the article refers to Next Generation Sequencing]
As a relative newcomer to the field of AS, I think it’ll be useful for me to delve into these articles – they seem to be a refreshing way to learn how quickly research into AS has ‘evolved’ as well as providing an honest outlook as to what areas seem to be a priority for future work.
The cover art in interesting too – it is entitled ‘Group in Sea, 1979, by Philip Guston‘. He was an American abstract expressionist painter.
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I’ve been working with Ally Wallace to develop cartoon-like drawings that illustrate our research – here is some work in progress. I like the lab soundscape in the background. The aim was to develop something that might appeal to a younger audience, and tries to take an imaginative approach to the subject. Maybe a bit too wordy, so I’m now doing much more stripped back drawings – these were all done on an iPad using the ProCreate app. Then again, maybe it would be better as a short pamphlet/book….let’s see.
I suppose ‘It’s About Time’ we actually posted something!
It’s taken us a while but hopefully this is the start of an interesting way to disseminate what we get up to in our labs and provide a sort of diary of our activities.
During the establishment of this blog we’ve talked a lot about how time and seasons seemed to be a huge influence on artists and songwriters (I’ve been introduced to the delights of Fairport Convention & The Incredible String Band, for example) and I’m sure that this will be a subject of future posts – Time and the passage of Time sure seems to get under our skins, no?